Publications (Last 5 Years)

  • Breves J, Hu M, Inokuchi M, Seale LA, Seale AP. (2026) Prolactin, cortisol, and extracellular osmolality regulate cftr, ostf1, and sgk1 in tilapia ionocytes. Front Endocrinol. Accepted [Link]

  • El-Aziz TM, Al-Sabi A, Seale LA, Soares AG. (2026) Current understanding of ENaC regulation by P2Y2/PLC/PI(4,5)P2 pathway. Purinergic Signalling 22(1): 2. DOI: 10.1007/s11302-025-10128-0. PMID: 41498836. PMCID: PMC12779786. [Link]

  • Shimada BK, Ogawa-Wong AN, Soares AG, Hallam KA, Santiago PJD, Saelua K, Nakahara-Akita K, Torres DJ, Brockmann JD, Kurokawa S, Ewell K, Bellinger MT, Toh P, Remedios GLP, Alfulaij N, Swanson S, Seyedali A, Zavacki AM, Berry MJ, Seale LA. (2026) Global loss of selenocysteine lyase in mice drives lipid accumulation in brown adipocytes. Am J Physiol Endocrinol Metab 330(2): E000. DOI: 10.1152/ajpendo.00213.2025. PMID: 41452587. PMCID: PMC12857770. [Link]
  • Santiago PJD, Shimada BK, Alfulaij N, Hallam KA, Soares AG, Young V, Swanson SM, Remedios GL, Toh P, Seale LA. (2025) Targeted disruption of selenocysteine lyase in brown adipocytes controls glutathione peroxidases 1 and 4 expression in males. Biol Trace Elem Res. DOI: 10.1007/s12011-025-04904-7. PMID: 41366172. [Link]

  • Shimada BK, Watanabe M, Takayama Apo NK, Soares AG, Hallam KA, Rivers O, Ewell K, Santiago PJD, Swanson SM, Toh P, Alfulaij N, Berry MJ, Seale LA. (2025) Cardiac redox imbalance upon disruption of selenocysteine decomposition in mice. Am J Physiol Heart Circ Physiol 329 (6): H1480-1496. DOI: 10.1152/ajpheart.00370.2025. PMID: 41134664. PMCID: PMC12734403. [Link]

  • Baranov P, Tierney J, Alba M, Andreev D, Aspden J, Atkins J, Bassani-Sternberg M, Berry MJ, (…)   Salzberg S, Seale LA, Seoighe C, Sergiev P, (…),  TRANSLACORE European Network. (2025) Translon: a single term for translated regions. Nature Methods 22(10): 2002-2006. DOI: 10.1038/s41592-025-02810-3. PMID: 40890551. [Link]

  • Lee KCY, Williams AL, Fujimoto A, Gerschenson M, Schuller C, Polgar N, Alfulaij N, Shimada BK, Seale LA, Shohet RV. (2025) PKM2 is a key regulator of cardiac lipid metabolism in mice. Mitochondrion 85:102070. DOI: 10.1016/j.mito.2025.102070. PMID: 40706825. PMCID: PMC12393220. [Link]

  • Shimada BK, Apo Takayama NK, Hallam KA, Santiago PJD, Yew JY, Alfulaij N, Nakahara-Akita K, Soares AG, Berry MJ, Seale LA. (2025) A selenomethionine deficient, high-fructose diet does not lead to cardiometabolic disorder in the selenocysteine lyase knockout mice. J Trace Elem Med Biol 90: 127685. DOI: 10.1016/j.jtemb.2025.127685. PMID: 40543467. PMCID: PMC12367225. [Link]

  • El-Aziz TM, Stockand JD, Seale LA, Mironova E, Soares AG. Gi-DREADD activation decreases Epithelial Na+ Channel activity in renal principal cells. (2025) Physiol Rep 13: e70433. DOI: 10.14814/phy2.70433. PMID: 40526015. PMCID: PMC12172568. [Link]

  • Seale LA, Yamanaka AB, Hammond K, Lim E, Wilkens LR, McFall P, Aflague TF, Coleman P, Fleming T, Shallcross L, Deenik J, Novotny R. (2025) Dietary micronutrient intake and the prevalence of metabolic conditions among children from the United States-Affiliated Pacific region in the Children’s Healthy Living Program. Curr Dev Nutr 2025 Jan; 9(1): 104531. doi: 10.1016/j.cdnut.2024.104531. [Link]

  • Chen Z, Inague A, Kaushal K, Fazeli G, Schilling D, Xavier da Silva TN, Dos Santos AF, Cheytan T, Freitas FP, Yildiz U, Viviani LG, Lima RS, Pinz MP, Medeiros I, Iijima TS, Alegria TGP, Pereira da Silva R, Diniz LR, Weinzweig S, Klein-Seetharaman J, Trumpp A, Mañas A, Hondal R, Bartenhagen C, Fischer M, Shimada BK, Seale LA, Chillon TS, Fabiano M, Schomburg L, Schweizer U, Netto LE, Meotti FC, Dick TP, Alborzinia H, Miyamoto S, Friedmann Angeli JP. (2024) PRDX6 contributes to selenocysteine metabolism and ferroptosis resistance. Mol Cell. 2024 Dec 5;84(23):4645-4659.e9. doi: 10.1016/j.molcel.2024.10.027. Epub 2024 Nov 14. PMID: 39547224. [Link]

  • Ralston NVC, Raymond LJ, Gilman CL, Soon R, Seale LA, Berry MJ. (2024) Maternal seafood consumption is associated with improved selenium status: Implications for child health. Neurotoxicology. 2024 Jan 23;101:26-35. doi: 10.1016/j.neuro.2024.01.003. PMID: 38272071.

  • Toh P, Seale LA, Berry MJ, Torres DJ. (2023) Prolonged maternal exposure to glucocorticoids alters selenoprotein expression in the developing brain. Front Mol Neurosci. 2023 Mar 24; 16:1115993. doi: 10.3389/fnmol.2023.1115993. PMID: 37033382; PMCID: PMC10080067. [Link]

  • An KJ, Hanato AN, Hui KW, Pitts MW, Seale LA, Nicholson JL, Toh P, Kim JK, Berry, MJ, Torres DJ. Selenium Protects Mouse Hypothalamic Cells from Glucocorticoid-induced Endoplasmic Reticulum Stress Vulnerability and Insulin Signaling Impairment. Antioxidants. 2023 Feb 20; 12(2), 526. doi: 10.3390/antiox12020526. PMID: 36830084; PMCID: PMC9952756. [Link]

  • Kawasaki NK, Suhara T, Komai K, Shimada BK, Yorichika N, Kobayashi M, Baba Y, Higa JK, Matsui T. The role of ferroptosis in cell-to-cell propagation of cell death initiated from focal injury in cardiomyocytes. Life Sci. 2023 Nov 1;332:122113. doi: 10.1016/j.lfs.2023.122113. Epub 2023 Sep 20. PMID: 37739163; PMCID: PMC10591893. [Link]

  • Toh P, Nicholson JN, Vetter AM, Berry MJ, Torres DJ. Selenium in Bodily Homeostasis: Hormones, Hypothalamus, and Highways of Communication. Int J Mol. Sci. 2022 Dec 6; 23(23), 15445. doi: 10.3390/ijms232315445. PMID: 36499772; PMCID: PMC9739294. [Link]

  • Shimada BK, Watanabe LM, Swanson S, Toh P, Seale LA. Selenium and selenoproteins in thermogenic adipocytes. Arch Biochem Biophys. 2022 Nov 30;731:109445. doi: 10.1016/j.abb.2022.109445. PMID: 36265651; PMCID: PMC9981474. [Link] 
  • Nicholson JL, Toh P, Alfulaij N, Berry MJ, Torres DJ. New insights on selenoproteins and neuronal function.  Free Radic Biol Med. 2022 Aug 7;190:55-61. doi: 10.1016/j.freeradbiomed.2022.07.021. PMID: 35948259 [Link]
  • Watanabe LM, Seale LA. Challenging Aspects to Precise Health Strategies in Native Hawaiian and Other Pacific Islanders Using Statins. Front Public Health. 2022 Feb 28;10:799731. doi: 10.3389/fpubh.2022.799731. PMID: 35296045; PMCID: PMC8918550. [Link]
  • Cardoso BR, Cominetti C, Seale LA. Editorial: Selenium, Human Health and Chronic Disease. Front Nutr. 2022 Jan 18;8:827759. doi: 10.3389/fnut.2021.827759. PMID: 35118114; PMCID: PMC8803728. [Link]
  • Torres DJ, Pitts MW. Pericytic porters: helping leptin step in. Trends Endocrinol Metab. 2021 Dec;32(12):958-959. doi: 10.1016/j.tem.2021.08.001. Epub 2021 Aug 19. PMID: 34420855; PMCID: PMC8764624. [Link]
  • Seale LA, Gilman CL, Zavacki AM, Larsen PR, Inokuchi M, Breves JP, Seale AP. Regulation of thyroid hormones and branchial iodothyronine deiodinases during freshwater acclimation in tilapia. Mol Cell Endocrinol. 2021 Dec 1;538:111450. doi: 10.1016/j.mce.2021.111450. PMID: 34506867; PMCID: PMC8551029. [Link]
  • Day K, Seale LA, Graham RM, Cardoso BR. Selenotranscriptome Network in Non-alcoholic Fatty Liver Disease. Front Nutr. 2021 Nov 17;8:744825. doi: 10.3389/fnut.2021.744825. PMID: 34869521; PMCID: PMC8635790. [Link]
  • Torres DJ, Pitts MW, Seale LA, Hashimoto AC, An KJ, Hanato AN, Hui KW, Remigio SMA, Carlson BA, Hatfield DL, Berry MJ. Female Mice with Selenocysteine tRNA Deletion in Agrp Neurons Maintain Leptin Sensitivity and Resist Weight Gain While on a High-Fat Diet. Int J Mol Sci. 2021 Oct 12;22(20):11010. doi: 10.3390/ijms222011010. PMID: 34681674; PMCID: PMC8539086. [Link]
  • Shimada BK, Alfulaij N, Seale LA. The Impact of Selenium Deficiency on Cardiovascular Function. Int J Mol Sci. 2021 Oct 2;22(19):10713. doi: 10.3390/ijms221910713. PMID: 34639053; PMCID: PMC8509311. [Link]
  • Watanabe LM, Hashimoto AC, Torres DJ, Alfulaij N, Peres R, Sultana R, Maunakea AK, Berry MJ, Seale LA. Effect of statin treatment in obese selenium-supplemented mice lacking selenocysteine lyase. Mol Cell Endocrinol. 2021 Aug 1;533:111335. doi: 10.1016/j.mce.2021.111335. PMID: 34052303; PMCID: PMC8263501. [Link]
  • Kiyohara ACP, Torres DJ, Hagiwara A, Pak J, Rueli RHLH, Shuttleworth CWR, Bellinger FP. Selenoprotein P Regulates Synaptic Zinc and Reduces Tau Phosphorylation. Front Nutr. 2021 Jul 1;8:683154. doi: 10.3389/fnut.2021.683154. PMID: 34277682; PMCID: PMC8280497.
  • Watanabe LM, Navarro AM, Seale LA. Intersection between Obesity, Dietary Selenium, and Statin Therapy in Brazil. Nutrients. 2021 Jun 12;13(6):2027. doi: 10.3390/nu13062027. PMID: 34204631; PMCID: PMC8231251. [Link]
  • Torres DJ, Yorgason JT, Andres MA, Bellinger FP. Methamphetamine Exposure During Development Causes Lasting Changes to Mesolimbic Dopamine Signaling in Mice. Cell Mol Neurobiol. 2021 Jun 17:10.1007/s10571-021-01120-4. doi: 10.1007/s10571-021-01120-4. PMID: 34138411; PMCID: PMC8678368.
  • Kremer PM, Torres DJ, Hashimoto AC, Berry MJ. Sex-Specific Metabolic Impairments in a Mouse Model of Disrupted Selenium Utilization. Front Nutr. 2021 May 10;8:682700. doi: 10.3389/fnut.2021.682700. PMID: 34041261; PMCID: PMC8141863. [Link]
  • Kilonzo VW, Sasuclark AR, Torres DJ, Coyle C, Pilat JM, Williams CS, Pitts MW. Juvenile Selenium Deficiency Impairs Cognition, Sensorimotor Gating, and Energy Homeostasis in Mice. Front Nutr. 2021 May 7;8:667587. doi: 10.3389/fnut.2021.667587. PMID: 34026810; PMCID: PMC8138326.
  • Torres DJ, Alfulaij N, Berry MJ. Stress and the Brain: An Emerging Role for Selenium. Front Neurosci. 2021 Apr 15;15:666601. doi: 10.3389/fnins.2021.666601. PMID: 33935643; PMCID: PMC8081839.
  • Torres DJ, Yorgason JT, Mitchell CC, Hagiwara A, Andres MA, Kurokawa S, Steffensen SC, Bellinger FP. Selenoprotein P Modulates Methamphetamine Enhancement of Vesicular Dopamine Release in Mouse Nucleus Accumbens Via Dopamine D2 Receptors. Front Neurosci. 2021 Apr 13;15:631825. doi: 10.3389/fnins.2021.631825. PMID: 33927588; PMCID: PMC8076559.

  • Galton VA, Larsen PR, Berry MJ. The Deiodinases: Their Identification and Cloning of Their Genes. Endocrinology. 2021 Mar 1;162(3):bqab005. doi: 10.1210/endocr/bqab005. PMID: 33449107; PMCID: PMC7864002.

  • Fujimoto BA, Young M, Nakamura N, Ha HY, Carter L, Pitts MW, Torres DJ, Noh HL, Suk S, Kim JK, Polgar N. Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model. J Biol Chem. 2021 Feb 27;15:100482. doi: 10.1016/j.jbc.2021.100482. PMID: 33647317; PMCID: PMC8027262. [Link]

  • Seale LA, Ogawa-Wong AN, Watanabe LM, Khadka VS, Menor M, Torres DJ, Carlson BA, Hatfield DL, Berry MJ. Adaptive Thermogenesis in a Mouse Model Lacking Selenoprotein Biosynthesis in Brown Adipocytes. Int J Mol Sci. 2021 Jan 9;22(2):611. doi: 10.3390/ijms22020611. PMID: 33435397; PMCID: PMC7827413. [Link]